Ultrafine powder is the basis of improving drug efficacy. Micro-powder of Western medicine can improve drug efficacy and reduce drug dosage. The same is true of traditional Chinese medicine, after the cell level micro-pulverization, the cell wall breaking greatly improves the efficacy.
At present, the ultrafine pulverization of traditional Chinese medicine mainly refers to the cell level micro-pulverization. The main pharmacodynamic components of animal and plant drugs are usually distributed within and between cells, and are mainly intracellular. When the cell breaks the wall, the active ingredients in the cell are exposed, so the efficacy is greatly improved, and the effect is fast. The equipment that can do this work is only vibration mill, ball mill and planetary mill three kinds of internationally recognized ultrafine grinding equipment.
Due to the low production efficiency of the ball mill, the grinding time is long, generally can not be used, although the planetary mill production efficiency is high, but the single capacity is too small, and the use of inconvenience, so it is not used, and the sea source ultrafine grinder is ultrafine grinding equipment. It is used for spore structure of plants (particle size only 10μm), such as ganoderma lucidum spore powder wall breaking can be completed in a very short time, its wall breaking rate of 95%, for any Chinese medicine can be ultrafine grinding. Haiyuan ultrafine Powder equipment has carried out ultrafine crushing of hundreds of Chinese herbs with great success. Among them, very difficult drugs such as blood and ganoderma lucidum can be ultrafine crushed. For mineral drug crushing up to 0.3 micron.
It is recognized that the international research can not reach D50<3μm, the machine is only a micro grinding equipment, not a micro grinding equipment, and it is very difficult to crush fiber and toughness Chinese medicine. In particular, there is a relatively high speed air flow during the crushing operation, which takes away the volatile components of the drug and causes the loss of the drug effect, so the machine is suitable for the micro crushing of chemicals with a certain brittleness, or the crushing of mineral Chinese medicine, and is not suitable for the micro crushing of animal and plant Chinese medicine.
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