At present, the ultrafine pulverization of traditional Chinese medicine mainly refers to the cell level micro-pulverization. The main pharmacodynamic components of animal and plant drugs are usually distributed in the intracellular and intercellular substance, and mainly in the intracellular. When the cell breaks the wall, the active ingredients in the cell are exposed, so the efficacy is greatly improved, and the effect is fast. At present, the domestic development of ball mill, planetary mill, rotor grinding, air grinding and vibration grinding technology and equipment.
Ball mill materials have wide adaptability, low cost, convenient operation and maintenance, and good equipment reliability, but the equipment efficiency is too low, and it is not competent for powder processing of high toughness and fiber materials.
Although the planetary mill has high production efficiency, the single-machine capacity is too small and inconvenient to use, so it is not used much. At present, the ultrafine grinding of animal and plant drugs in Germany and Japan are all using vibration grinding. But the vibration mill has one, two, three generations, only the third generation of vibration mill is ultrafine grinding equipment. It is used for spore structure of plants (particle size only 10μm), such as ganoderma lucidum spore powder wall breaking can be completed in a very short time, its wall breaking rate can reach 95%, for any Chinese medicine can be ultrafine grinding. For mineral drug crushing up to 0.3 micron.
It is recognized that the international research can not reach D50<3μm, the machine is only a micro grinding equipment, not a micro grinding equipment, and it is very difficult to crush fiber and toughness Chinese medicine. In particular, there is a relatively high speed air flow during the crushing operation, which takes away the volatile components of the drug and causes the loss of the drug effect, so the machine is suitable for the micro crushing of chemicals with a certain brittleness, or the crushing of mineral Chinese medicine, and is not suitable for the micro crushing of animal and plant Chinese medicine.
The existence of a variety of rotary mill with screen head, can not guarantee the whole components into medicine, can not be used for micro crushing of traditional Chinese medicine, especially the crushing of compound Chinese medicine. It is suitable for crushing operation in chemical industry.
It is very important to choose a reasonable grinding equipment for the ultrafine grinding of traditional Chinese medicine.
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