Wet Granulation Machine
introduction:
Wet granulation machine is a vital equipment used in the pharmaceutical industry for the formation of granulated mixtures. This machine is used to improve the flowability and compressibility of dry powders, making them more suitable for the manufacturing of tablets and other solid dosage forms.
The wet granulation machine works by mixing the dry powder with a liquid binder, typically water or an organic solvent, to form a wet mass. The wet mass is then passed through the machine, which compresses and forms it into granules. These granules are then dried and screened to remove any lumps or aggregates before being used in the production of tablets.
technical parameters:
|
Capacity(L) |
50 |
100 |
150 |
200 |
250 |
300 |
400 |
600 |
800 |
|
Output(kg/batch) |
15 |
35 |
50 |
70 |
85 |
100 |
130 |
200 |
260 |
|
Admix speed(rpm) |
0-400 |
0-400 |
0-270 |
0-270 |
0-250 |
0-230 |
0-190 |
0-170 |
0-120 |
|
Admix power(kw) |
5.5 |
7.5 |
11 |
15 |
18.5 |
22 |
30 |
37 |
45 |
|
Incise speed(rpm) |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
0-2900 |
|
Incise power |
2.2 |
3 |
4 |
5.5 |
5.5 |
7.5 |
11 |
11 |
15 |
FAQ
1. Q: What is wet granulation machine?
A: Wet granulation machine is a pharmaceutical processing equipment used to turn powdered or granulated materials into granules. It is commonly used in the pharmaceutical industry for the production of tablets.
2. Q: How does wet granulation machine work?
A: Wet granulation machine works by mixing a powdered or granulated drug substance with a liquid binder to form a wet mass. The wet mass is then forced through a sieve to produce wet granules. The wet granules are then dried to produce the final product.
3. Q: What are the advantages of using wet granulation machine?
A: Wet granulation machine offers several advantages compared to other granulation methods. Firstly, it produces granules with excellent flow properties, which leads to improved tablet compression and handling. Secondly, wet granulation machine allows for the incorporation of multiple drug substances, which can improve drug efficacy and reduce side effects. Lastly, wet granulation machine is a highly flexible process that can be adapted to different drug substances and formulations.
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